Pri Etz Chaim relates him to Elagabalism and states that holiness was only found in the head of Esav. See [[התלי]].
Ramchal in Kinat HaShem Tzevato says And understand that Esav could have been holy and they would both be good sons to HaShem... Know that two things need to be done: One - repairign holiness in the secrret of spreadding its steps and the other - the buinding ot the sitra achra UNDER holiness.
Three grandsons of Esau were Teman, Omar and Amalek.