According to the Otiyot de-Rabbi Aqiva, on the Letter Tsade, the two horns of the letter Tsade refer to Ye.Sh.U. NoTzRY who took hold of two heads, Jacob and Edom, and caused people to Err.
In the Persian Yosef al-hamaden 's Ta'amei haMitzvot calls him an abominable detestable villain and evil person.